Does the Naked Mole Rat have the Power to STOP Cancer?

The underground naked mole rat has been found to produce a hybrid protein that prevents tumour growth. The discovery was made by scientists at the University of Rochester in New York.

The protein is associated with a cluster of genes (called a locus) that is also found in humans and mice. It is the job of that locus to encode several cancer-fighting proteins. The locus found in naked mole rats encodes a total of four cancer-fighting proteins, while the human and mouse version encodes only three.

Despite their names, naked mole rats are neither moles nor rats (nor are they totally hairless). These remarkable creatures are more closely related to porcupines and guinea pigs. They are subterranean rodents that have never been known to get cancer despite having a 30-year lifespan.

Naked mole rats live in the horn of Africa and are native to Somalia, Ethiopia and Kenya. They’re not blind, yet their eyes are very small and naked mole rats will often close them when they run through the tunnels.

The findings by Seuanov and Gorbunova research team have been published in the Proceedings of the National Academy of SciencesIn an effort to determine whether the effective protein is also found in mice and humans, the researchers tried to screen mouse and human cells and tissues for the protein hybrid, but were unsuccessful. “While our work doesn’t eliminate the possibility that the protein exists under some conditions in mice and humans, the results suggest that it’s highly unlikely,” said Gorbunova.

Tests have shown that the protein can prevent human cells from turning cancerous, and researchers hope to use it develop new treatments in the future for patients with cancer.

Image credit: Jedimentat44

On & On We Grow – Introducing Liz Holdsworth

At Kinetica, we are always on the hunt for new talent to join our team and have recently had the pleasure of recruiting our newest member – Liz Holdsworth.

Liz has five years’ experience in the recruitment industry – four of which have been spent in the pharmaceutical and medical device markets.

Since joining Kinetica, Liz has focussed her efforts purely in the pharmaceutical sector, as this is where her strongest professional relationships have been built with clients and candidates alike.

With a genuine interest in the pharmaceutical industry, Liz can often be found pouring over articles and news items on the movements and progress of technology and science in this area.

Liz specialises in mid to senior level appointments, covering functions such as: Quality & Regulatory, Technical, R&D, Engineering & Manufacturing, Sales & Marketing, Operations Management and Continuous Improvement. She recruits both permanent and contract roles, and geographically covers the UK and Europe (Liz is also SECO registered for Swiss recruitment.)

Liz is a proven headhunter and a large majority of her work is exclusive or retained due to her impressive success rates. She has never placed a candidate in a role that didn’t prove fruitful, and can boast of 100% rebate-free track record.

If you are seeking an opportunity in the pharmaceutical sector, give Liz a call on 0113 261 71 81 or email liz.holdsworth@kinetica.co.uk or connect with her on LinkedIn here.

Liz Holdsworth